Aug 16, 2018
This episode covers a rare but life-threatening complication of
lupus nephritis called complement-mediated thrombotic
microangiopathy. Rheumatologist Lisa Zickuhr, MD,
helps us better understand this often-overwhelming topic with a
clinical case example, treatment options and practice pearls.
- Intro :10
- Introduction of Lisa Zickuhr, MD, rheumatologist
- Complement-mediated thrombotic microangiopathy in lupus is an
overwhelming topic 1:50
- Definition of TMA 2:15
- What is MAHA? 3:10
- Four classic symptoms associated with TMA syndromes
- What causes TMA? 3:50
- Complement-mediated TMA 5:35
- How this is seen in clinical practice
- Case example of complement-mediated TMA
- Summary of case presentation
- What’s next? 13:50
- Takeaways from this clinical presentation
- Primary and secondary complement-mediated TMA
- An argument for a primary etiology of complement-mediated TMA
in lupus 18:51
- CliffsNotes version for rheumatologists, HCPs caring for lupus
- Therapy for complement-mediated TMA is two-pronged
- Patient profile 24:05
- Summary 25:10
- Thank you to Dr. Lisa Zickuhr
Lisa Zickuhr, MD, is a rheumatologist at
Washington University in St. Louis.
We’d love to hear from you! Send your comments/questions to
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