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Rheuminations

Nov 27, 2019

Things get a little nerdy in this episode, which focuses on the basic science of what makes the inflammasome tick in CAPS, as well as data on the use of interleukin 1 inhibition.
Hint: Listen to “The Inflammasome for Dunces” episode first, and this one will make more sense.

  • Intro :20
  • Recap of Part 1 :33
  • Overview of...


Nov 7, 2019

This first episode delves into the clinical aspects of the Cryopyrin-Associated Periodic Syndromes and includes some helpful tips for sorting out some of the autoinflammatory diseases in the spectrum.

  • Intro :10
  • Cryopyrin-Associated Periodic Syndromes (CAPS) :25
  • Outline of Part 1 2:25
  • What is CAPS? 3:12
  • Case #1 – a...


Oct 1, 2019

A quick take on one of the little-appreciated engines of the innate immune system. 

  • Intro :10
  • A little about this episode :25
  • The inflammasome is a component of the innate immune system 3:12
  • Remember NLRP3 4:12
  • The toll-like receptors 5:05
  • Triggering the inflammasome 7:05
  • The proteins 8:04
  • A medieval battle and a...


Aug 9, 2019

“Acute rheumatic fever is proceeded by an infection with Group A strep” is a mantra that all health care workers know. This episode digs through the history of how we came to understand this fact, as well as how our understanding of the pathophysiology and treatment of rheumatic fever developed.

  • Intro :10
  • Why I...


Aug 1, 2019

Join me as I explore a case of fever and migratory inflammatory arthritis, then discuss the case with the double-boarded rheumatologist/infectious disease expert, Cassandra Calabrese, DO.

  • Intro :10
  • My new book :24
  • Inside this episode 1:20
  • Case presentation 1:38
  • Introducing Dr. Cassandra Calabrese 9:22
  • The interview...