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Feb 20, 2020

Checkpoint inhibitors have changed the field of oncology, as well as our understanding of autoimmunity. This episode, hosted by Leonard H. Calabrese, DO, walks us through the history of checkpoint inhibitors — from Dr. William Coley’s use of infections in cancer to the development of PD-1 inhibitors.

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Jan 27, 2020

Join Peter Grayson, MD, MSc, and I as we discuss a range of topics, including imaging in large-vessel vasculitis, doctors going into research, Twitter, rock ‘n’ roll and Disney World.

  • Intro :10
  • A bit about Peter Grayson :55
  • Come see me in Phoenix in February 3:35
  • The interview 4:07
    • How did you make it to the...

Dec 18, 2019

This interview with Chester V. Oddis, MD, will have you standing from a seated position without the need to use your arms as we discuss the inflammatory myopathies. We cover the classification, pathophysiology and treatment approaches to these diseases, as well as all the antibodies you must learn about...

Nov 27, 2019

Things get a little nerdy in this episode, which focuses on the basic science of what makes the inflammasome tick in CAPS, as well as data on the use of interleukin 1 inhibition.
Hint: Listen to “The Inflammasome for Dunces” episode first, and this one will make more sense.

  • Intro :20
  • Recap of Part 1 :33
  • Overview of...

Nov 7, 2019

This first episode delves into the clinical aspects of the Cryopyrin-Associated Periodic Syndromes and includes some helpful tips for sorting out some of the autoinflammatory diseases in the spectrum.

  • Intro :10
  • Cryopyrin-Associated Periodic Syndromes (CAPS) :25
  • Outline of Part 1 2:25
  • What is CAPS? 3:12
  • Case #1 – a...