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Rheuminations


May 20, 2020

This episode dives into the rare Whipple’s disease, focusing on the articular manifestations of this infectious masquerader and when a rheumatologist should consider it in the differential.

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  • Intro :20
  • In this episode :28
  • Background on the organism 5:25
  • An important point when making the diagnosis 7:48
  • Who gets infected? 8:55
  • What is Whipple’s disease? 11:48
  • This disease is fatal 15:53
  • A look at the joints 16:28
  • What happens when you give these patients immunosuppression? 26:36
  • How to diagnose 28:38
  • Summary so far 31:00

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  • Other organ manifestations of Whipple’s disease 32:08
  • Summary and take-home 44:36

Disclosure: Brown reports no relevant financial disclosures.

We’d love to hear from you! Send your comments/questions to rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum

References:

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Raheja AA, et al. Clin Imaging. 2010;34:143-147.

Ramos JM, et al. J Med Case Rep. 2015;9:165.

Raoult D, et al. Emerg Infect Dis. 2010;16:776-82.

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Additional resource:

Neurosigns.org’s video on oculomasticatory myorhythmia can be viewed at: https://www.youtube.com/watch?v=Zwb5bt749Jo