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May 20, 2020

This episode dives into the rare Whipple’s disease, focusing on the articular manifestations of this infectious masquerader and when a rheumatologist should consider it in the differential.

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  • Intro :20
  • In this episode :28
  • Background on the organism 5:25
  • An important point when making the diagnosis 7:48
  • Who gets infected? 8:55
  • What is Whipple’s disease? 11:48
  • This disease is fatal 15:53
  • A look at the joints 16:28
  • What happens when you give these patients immunosuppression? 26:36
  • How to diagnose 28:38
  • Summary so far 31:00

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  • Other organ manifestations of Whipple’s disease 32:08
  • Summary and take-home 44:36

Disclosure: Brown reports no relevant financial disclosures.

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Additional resource:’s video on oculomasticatory myorhythmia can be viewed at: