Jul 10, 2018
Do you know which U.S. president had Addison’s disease? Or how
rumors from WWII led to funding for research on cortisol? In this
episode, take a trip down memory lane as we detail the history of
steroids and the scientists whose work lead to the discovery of
- Intro :14
- A query: What other disease is attributed to Thomas Addison?
- Overview of the layers of the adrenal gland
- History of the adrenal gland
- Thomas Addison enters the scene
- Kennedy and terminology 6:15
- Charles Brown-Sequard helps describe function of adrenal glands
- George Oliver and Edward Sharpey-Schafer help understand
adrenal gland 8:44
- Adrenaline is discovered 10:03
- Steroid chemistry begins in earnest
- Steroids discovered, but questions remain
- WWII rumors spur research on cortin
- Edward Calvin Kendall, Tadeus Reichstein and Philip Showalter
Hench receive Nobel prize for their discoveries relating to the
hormones of the adrenal cortex 12:23
- Committee of 14 chemists assembled
- 1948: The case of Mrs. G 15:21
- Pharmaceutical companies race to produce cortisone
- How we arrived at prednisone
- The answer to the question: “What other disease was described
by Thomas Addison?” 18:34
We’d love to hear from you! Send your comments/questions to
Benedek TG. Clin Exp Rheumatol.
Burns CM. Rheum Dis Clin North Am.
Lawrence L. Controversial ‘father’ of endocrinology:
Brown-Séquard. Endocrine Today. February 2008.
Accessed April 10, 2018.
Pearce JMS. J R Soc Med.