Oct 5, 2018
Do you know the etymology of the word “gout,” or how a simple
microscope aided in the identification of tophi? Join me as I
explore the history of this inflammatory arthritis and highlight
the important scientists who shaped the modern era of gout.
- Intro :10
- What to expect in Part 2 :48
- A question: Which urate-lowering therapy was made for an
expressly different reason than to treat gout?
- The first modern description of gout
- Let’s go back to the Greeks 3:05
- Why is it called “gout?” 3:06
- An anecdote from medical school
- Hippocrates’ words of wisdom on gout
- First century AD: Gout is linked with excessive eating and
- Things get muddled 6:20
- 1683: The modern era of gout is described
- “Gout Perspectives” published in The Lancet in 2018
- Self-taught Dutch scientist, Antony van Leeuwenhoek, pioneers
the microscope and identifies tophi
- Swedish chemist Carl Wilhelm Scheele discovers uric acid
- William Hyde Wollaston tests tophi and discovers it’s full of
uric acid 12:57
- Emperor of uric acid, Alfred Baring Garrod, associates elevated
serum uric acid with gout 13:48
- If anyone knows how the thread test works, please email me
- He theorized that uric acid causes gout
- A look back at what we know
- What we don’t know: What’s in the joints of patients with acute
- Stay tuned for The History of Gout, Part 2
We’d love to hear from you! Send your comments/questions to
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Simkin PA. Arthritis Res Ther. 2006;doi:
RW. Arch Intern Med. 1985;145:1492-1503.
Shyambhavee, Behera BK. J Pharmacol Clin Toxicol.
GD. Rheumatology. 2001;40:1189-1190.
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