Jan 21, 2021
Here I break down the confusing system that is the ire of medical learners who aim to memorize it, only to forget it later. Join me on a medieval journey that will help you visualize this complex system in a way that will stay with you.
Brought to you by GSK. Consider the long-term impact of disease activity flares and corticosteroid use on patients with active SLE. Learn more now at treatfortodayandtomorrow.com.
- Intro :10
- Welcome :24
- How do you explain the complement system? :44
- What is the complement system? 1:39
- How does it complement the adaptive immunity? 3:43
- Two major aspects of the complement system 4:50
- Formation of the membrane attack complex 5:21
- Why is this pathway so confusing? 5:55
- Why do I have to memorize all of this? 8:33
- Let’s talk about the cascades themselves 11:15
- Breaking down the three pathways 12:55
Brought to you by GSK. Considering a treatment change for patients with active SLE? Learn about a treatment option for your patients at treatfortodayandtomorrow.com.
- The alternative pathway – walking to the beat of its own drum 16:15
- A medieval tale of the classic and lectin pathway 22:36
- The tale of the alternative pathway 28:00
- Summary 31:55
- In the next episode 32:40
Disclosures: Brown reports no relevant financial disclosures.
We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum
References:
Music: The Medieval Banquet by Shane Ivers - https://www.silvermansound.com