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Rheuminations

Oct 15, 2020

The last episode in the series highlighting how the structure of the antibody was discovered, as well as how a chicken butt was critical in understanding B cell biology.

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Oct 2, 2020

Learn about the discovery of immunodeficiencies leading to the use of pooled immunoglobulin as therapy, the struggle to use it intravenously and the eventual use in autoimmune disease.

  • Intro :11
  • In this episode :15
  • Splitting Part 3 into two episodes :26
  • Part A of the history of IV Ig and the antibody :53
  • A recap on...


Aug 18, 2020

Part 2 of this series explores how we began to measure antibody levels and how serotherapy evolved and was used to investigate multiple diseases (I’m looking at you, pneumonia). We’ll also learn how advances in laboratory techniques like electrophoresis paved the way for a better understanding of the...


Jul 15, 2020

COVID-19 has brought up the use of the old remedy convalescent serum. What is it? Did it work? This series walks us through the history of the serum, how it was discovered, how it was first used, and how it inspired the field of immunology.

  • Intro :11
  • In this episode :15
  • A quick tale :20
  • Outline of these three...


Jun 22, 2020

With COVID-19 and the question of whether glucocorticoids could be beneficial, this episode digs into the data on the use of glucocorticoids in the setting of infections, from pneumonia and septic arthritis, to meningitis and septic shock.

  • Intro :11
  • In this episode :25
  • The first published case series of patients with...